- TB-500
Sprayable bioadhesive microcarriers loaded with Tβ4-Engineered ADSC exosomes for diabetic wound healing.
Ding Y et al. · Bioactive materials
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Peptide knowledge hub
An index of published studies and press coverage about research peptides. The work is other people's. Listing it here is not a claim about the products sold on this site, and it is not an endorsement.
Entries are collected automatically from PubMed and from publisher feeds, by search query and date, before their results are known. Null and negative findings are listed alongside the rest. The one-line description under each entry is written by a language model from the paper's abstract: it describes how a study was run and, where the paper states an outcome, what the paper reported — never a claim of our own.
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Seven papers on MOTS-c arrived this period, the largest cluster, and they span mice, rats and cells. Four looked at injury or stress in mice: muscle wasting from a tumour, lung damage from radiation, hearts exposed to high oxygen at birth, and an abdominal MRSA infection. Two used rats, one with diabetes and one with surgically created skin flaps, and one used mice with induced atrial fibrillation. The researchers measured things like muscle mass, inflammatory markers, heart rhythm inducibility and tissue survival, and compared treated animals against untreated ones.
Four papers on BPC-157, three in rats and one review of human data. The rat studies covered a lower-limb injury from restricted then restored blood flow, a cut and repaired Achilles tendon tested at four weeks, and rats with one adrenal gland removed. The human review pooled three small studies covering 30 people, with the peptide given into the knee joint, into the bladder or into a vein, and looked at reported symptom changes and
38 matching records
Ding Y et al. · Bioactive materials
View on PubMed(opens in a new tab)Study design: review
Zhao Z et al. · European journal of pharmacology
View on PubMed(opens in a new tab)Study design: review
Thirty people across three small studies were given BPC-157 — by injection into the knee joint, into the bladder, or into a vein — and the review looked at reported symptom changes and side effects.
Poolton JT et al. · Acta orthopaedica Belgica
View on PubMed(opens in a new tab)Male rats with streptozotocin-induced diabetes were given retatrutide, and their learning and memory were tested using water maze and avoidance tasks, along with measures of brain inflammation and tissue structure.
Keskin U et al. · Behavioural brain research
View on PubMed(opens in a new tab)Study design: review
Demirtaş H · International journal of molecular sciences
View on PubMed(opens in a new tab)Study design: review
Mokhtar J et al. · Aesthetic surgery journal
View on PubMed(opens in a new tab)Mice with an abdominal MRSA infection were given MOTS-c, a peptide encoded by mitochondrial DNA, and the researchers compared how the infection progressed in treated and untreated animals.
Rice MC et al. · eLife
View on PubMed(opens in a new tab)Newborn mice exposed to high oxygen were given MOTS-c, and the paper reports that their hearts showed less thickening, scarring, and loss of function than hearts of mice not given the compound.
Li SH et al. · Life sciences
View on PubMed(opens in a new tab)Rats made diabetic with a high-fat diet and a drug that damages the pancreas were given MOTS-c, and the researchers measured their fasting blood sugar, inflammation markers in the blood, and stained heart tissue for signs of inflammatory activity.
Mills AR et al. · Experimental physiology
View on PubMed(opens in a new tab)Rats with surgically cut and repaired Achilles tendons were given BPC-157, TB-500, or both for four weeks, and their tendons were then tested for how much force they took before tearing and examined under a microscope.
Biçer O et al. · Joint diseases and related surgery
View on PubMed(opens in a new tab)Najafi N et al. · Archives of internal medicine research
View on PubMed(opens in a new tab)Mice with spermatogenic damage from simulated microgravity were given MOTS-c, and the paper reports that it reduced oxidative stress and cell death in the testes, preserving sperm production.
Liu S et al. · Free radical biology & medicine
View on PubMed(opens in a new tab)Mice exposed to radiation that damages the lungs were given daily injections of an engineered peptide called R13A-MOTS-c for two weeks, and the researchers measured inflammation, oxidative damage, and mitochondrial function in their lung tissue.
Zhang YL et al. · Redox biology
View on PubMed(opens in a new tab)Human HaCaT keratinocytes, a laboratory skin cell line, were stimulated with TNF-α and IFN-γ and then given a Torilis japonica extract combined with GHK-Cu, and the researchers measured Th2 cytokine and chemokine transcription, IgE production, radical scavenging, and cell migration in a wound healing assay.
Jeon S et al. · Antioxidants (Basel, Switzerland)
View on PubMed(opens in a new tab)Xing L et al. · Inflammation and regeneration
View on PubMed(opens in a new tab)Study design: review
Amado CA et al. · Journal of translational medicine
View on PubMed(opens in a new tab)Santhanam SS et al. · Molecular biology reports
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